Figure1 Synthesis of archaeosine in tRNA (IMAGE)

Ehime University

Figure1 Synthesis of archaeosine in tRNA

Caption

Archaeosine is synthesized via three steps in tRNA.  ArcS, the second-step enzyme, transfers a lysine to preQ0, which is introduced into tRNA by ArcTGT, the first-step enzyme.  The resultant preQ0-Lys in tRNA is further converted to archaeosine by RaSEA, the third-step enzyme.  In this study, the enzymatic properties of ArcS have been investigated.

Credit

Hiroyuki Hori, Shu Fujita, Ehime University

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