Psilocybin-1-main (VIDEO) Washington University School of Medicine This video is under embargo. Please login to access this video. Caption This heat map of brain activity patterns shows profound disturbance during an individual’s experience after taking psilocybin. Relatively stable patterns before and after the dose (blue and green hues) are temporarily scrambled during the "trip" (red, orange and yellow hues). Researchers at Washington University School of Medicine in St. Louis report that psilocybin destabilizes a critical network of brain areas involved in introspective thinking. The findings provide a neurobiological explanation for the drug’s mind-bending effects. Credit Sara Moser/Washington University Usage Restrictions This image is to be used in accordance with the mission, policies and guidelines of Washington University in St. Louis. Visit https://wustl.edu/about/compliance-policies/media-policies/multimedia-use/ for more information. License Original content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.