A schematic for generating C@ECN-PL and the mechanism of its antitumor activity (IMAGE)
Caption
C@ECN-PL delivers CXB to tumor cells via liposomes anchored to the cell surface and promotes immune cell recruitment to the tumor. The self-lysis circuit ensures that C@ECN-PL does not accumulate within the tumor microenvironment. CXB and DOX suppress anti-apoptotic gene expression within tumor cells.
Credit
BioDesign Research
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Credit must be given to the creator.
License
CC BY