Scabrolide F and its synthetic intermediates (IMAGE)
Caption
The synthetic scabrolide F and its related compounds showed antifouling activity toward the cypris larvae of the barnacle Amphibalanus amphitrite with EC50 values of 2.65–9.46 μg/mL. Furthermore, these six compounds were found to be nontoxic at a concentration of 50 μg/mL (LC50 > 50 μg/mL).
Credit
Hiroyoshi Takamura from Okayama University
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