PKM KIBRA Structures with Inhibitors (IMAGE)

New York University

PKM KIBRA Structures with Inhibitors

Caption

Memories are stored by the interaction of two proteins: a structural protein, KIBRA (green), that acts as a persistent synaptic tag, and a synapse-strengthening enzyme, protein kinase Mzeta (red). Drugs that disrupt the memory-perpetuating interaction (other colors) erase pre-established long-term and remote memories. 

Credit

Changchi Hsieh, Ph.D.

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Use with this study only

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