RAI2 and CtBP stack (IMAGE) European Molecular Biology Laboratory Caption A visual metaphor depicting the unstructured protein RAI2 (parts of it visible in orange), as it disables the cancer-promoting CtBP protein (green) by stacking its molecules up into an elongated polymer which forms aggregates in cells. This process may play a role in how cancer progresses to become treatment resistant. Credit Isabel Romero Calvo/EMBL Usage Restrictions Credit must be given to the creator. Adaptations must be shared under the same terms. License CC BY-SA Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.