Deep-physics-informed sparsity framework universally extends the spatial resolution of structured illumination microscopy for different biological samples (IMAGE)
Caption
(A–C) Representative images reconstructed by conventional method (left) and new method (right) of microtubules, nuclear pore complexes and F-actin samples. The regions enclosed by the white boxes are magnified and shown below with intensity profiles along corresponding indicators. (D) A representative clathrin-coated pit image reconstructed by conventional method (left) and new method (right). Magnified views of the region enclosed by the white box are shown on the right with intensity profiles along corresponding lines. (E) Dynamic activity of a representative growing clathrin-coated pit observed by conventional method (top) and new method (bottom). (F) Statistical resolution comparisons of conventional method and new method in the cases of clathrin-coated pit, microtubule and F-actin samples.
Credit
Zitong Ye et al.
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CC BY