TIMP-1 Promotes Expression of MCP-1 and Macrophage Migration by Inducing Fli-1 in Experimental Liver Fibrosis (IMAGE)

Xia & He Publishing Inc.

TIMP-1 Promotes Expression of MCP-1 and Macrophage Migration by Inducing Fli-1 in Experimental Liver Fibrosis

Caption

TIMP-1 induces Fli-1 expression through miRNA-145, subsequently increasing MCP-1 expression and macrophage recruitment. MiRNA-145-enriched EVs from HSCs can transmit biological information and magnify the function of TIMP-1.

Credit

Min Cong, Xiaoli Huang, Xiaofan Wang, Yanhong Wang

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Credit must be given to the creator. Only noncommercial uses of the work are permitted.

License

CC BY-NC

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