Small animal SPECT/CT images comparing 177Lu-L804-IAB2MA and 177Lu-DOTA-IAB2MA, and small animal PET/CT images comparing 89Zr-L804-IAB2MA and 89Zr-DFO-IAB2MA. (IMAGE)

Society of Nuclear Medicine and Molecular Imaging

Small animal SPECT/CT images comparing 177Lu-L804-IAB2MA and 177Lu-DOTA-IAB2MA, and small animal PET/CT images comparing 89Zr-L804-IAB2MA and 89Zr-DFO-IAB2MA.

Caption

Figure 1. Small animal SPECT/CT images comparing 177Lu-L804-IAB2MA and 177Lu-DOTA-IAB2MA, and small animal PET/CT images comparing 89Zr-L804-IAB2MA and 89Zr-DFO-IAB2MA. These images demonstrate similar tumor targeting and improved clearance of 177Lu-L804-IAB2MA compared to 177Lu-DOTA-IAB2MA, while showing comparable performance of 89Zr-L804-IAB2MA and 89Zr-DFO-IAB2MA.

Credit

Images created by V Ho, D Tatum, D Magda, and CJ Anderson, University of Missouri-Columbia and Lumiphore (Berkeley, CA).

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