Ultra-High-Resolution PET Provides Never Before Seen Images of the Brain (IMAGE)
Caption
Figure 1. A. 18F-SynVesT-1 images at early (0-10) and late (90-120 minute) times postinjection. There is clear identification of high flow regions in the early images. The late images show the synaptic (SV2A) pattern which differs from the flow pattern, e.g., in the thalamus. B. 11C-PHNO binding potential (BPND) images shown in transverse, coronal, and sagittal orientations of PET alone and PET overlaid with MRI. Left: Region of substantia nigra (green arrow, max display: 4.0). Right: Thalamic region (max: 2.5) showing focal bilateral binding in a specific thalamic nucleus (blue arrow, likely anteroventral nucleus). C. Sagittal images of 11C-LSN3172176 M1 muscarinic cholinergic BPND (max display: 10). D. R1 images of the same tracer (max: 2). Cerebellum (blue arrow) shows no specific binding (C) and high tracer delivery (D). E. 18F-FE-PE2I dopamine transporter BPND images (zoomed, max display: 6) showing striatum and substantia nigra (green arrow). F. R1 images of the same tracer (max: 2) with inset showing zoomed region in E.
Credit
Images created by Richard E. Carson, et al., Yale University, New Haven, CT.
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