Fabrication of hydrogel sealant for sealing and repairing defects in cerebral and lumbar dura mater (IMAGE)

Science China Press

Fabrication of hydrogel sealant for sealing and repairing defects in cerebral and lumbar dura mater

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(a) Hydrogel sealant is fabricated by simply mixing gelatin with o-phthalaldehyde terminated four-arm poly(ethylene glycol) (4aPEG-OPA). (b) Mechanisms of crosslinking in bulk hydrogel and adhesion between hydrogel and tissue surface. (c) Sealing of cerebral and lumbar dural defects with hydrogel sealant.

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