Mutated amino acids in the AFF3 protein found in KINSSHIP syndrome patients and their interaction partners. (IMAGE)

University of Lausanne

Mutated amino acids in the AFF3 protein found in KINSSHIP syndrome patients and their interaction partners.

Caption

Model showing the interaction between a portion of the AFF3 protein (in white) and ubiquitin ligase (in green and gold), the protein that regulates its degradation. Amino acids mutated in KINSSHIP syndrome patients are shown as yellow atoms. The ubiquitin ligase amino acids with which they interact are depicted as colored atoms.

Credit

Nicolas Guex © UNIL

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