Mathematical Model Describing Patient-Specific Tumor Dynamics to Guide Treatment Dose Scheduling (IMAGE)

National Research Council of Science & Technology

Mathematical Model Describing Patient-Specific Tumor Dynamics to Guide Treatment Dose Scheduling

Caption

A mathematical model describes tumor dynamics where the tumor comprises drug-sensitive cancer cells (S), -resistant cancer cells (R), and plastic cancer cells (P). The model proposes evolutionary therapy dosing cycling, alternating between treatment off, minimum effective dose, and maximum tolerated dose. This schematic illustrates the anticipated changes in tumor composition following the administration of the proposed dosing cycles.

Credit

Korea Institute of Science and Technology(KIST)

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