Functional MRI brain maps of resting-state functional connectivity (IMAGE)
Caption
Functional MRI brain maps of resting-state functional connectivity in representative age- and sex-matched participants. (A, B) Axial (top) and coronal (bottom) views show whole-brain connectivity, with the seed at the left (L) superior frontal region, in a 36-year-old female participant in the low-level light therapy (LLLT) treatment group (A) and a 38-year-old female participant in the sham treatment group (B) during the acute, subacute, and late-subacute phases (columns, from left to right, in both A and B) of traumatic brain injury recovery. (C) Axial (top left), coronal (bottom left), and sagittal (right) views in a 38-year-old female control participant are shown for comparison; the solid green circle in the sagittal view indicates the location of the left superior frontal seed region. The color bar indicates that brain regions with warm colors (red, orange, yellow) show resting-state fluctuations that have significant positive correlation (r of 0 to 1) with those of the left superior frontal region, and brain regions with cold colors (blue) show resting-state fluctuations that have significant negative correlation (r of −1 to 0) with those of the left superior frontal region. Brain regions that have functional connectivity with the left superior frontal seed in the LLLT-treated participant (arrowheads in A) but not in the sham-treated participant (arrowheads in B) are shown. The arrow in A additionally shows brain regions with positive correlation with the seed in the LLLT-treated participant, but negative correlation with the seed in the sham-treated participant (arrow in B).
Credit
Radiological Society of North America (RSNA)
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May use with credit.
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