Thalidomide derivatives (IMAGE)

Goethe University Frankfurt

Thalidomide derivatives

Caption

The thalidomide derivatives C5, C6 and C7 alter CRBN – the “labeling machine” – so that it can bind to BCL-2. In this way, the BCL-2 molecule is marked for degradation – a possible new strategy against cancer.

Credit

Dr. Xinlai Cheng, Goethe University Frankfurt

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To be used only when reporting on Goethe University Frankfurt. Indicate copyright: Dr. Xinlai Cheng, Goethe University Frankfurt

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