TP53 inactivation initiates ordered genomic evolution. (IMAGE) China Anti-Cancer Association Caption TP53 inactivation initiates ordered genomic evolution. Credit Cancer Biology & Medicine Usage Restrictions Credit must be given to the creator. License CC BY Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.