Figure (IMAGE)

Osaka University

Figure

Caption

The IAE pathogenesis, with severe brain edema caused by IAV, could be established without viral proliferation: Influenza virus protein was produced and accumulated in the influenza virus-infected endothelial cells (EC). Without producing daughter virus, accumulated viral protein induced necrosis of EC and disruption of blood-brain barrier leading to vascular leakage and bleeding.

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©2024 Kimura-Ohba

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