Figure 1 (IMAGE)
Caption
Astrocyte activity precedes the onset of epileptic neuronal hyperactivity episodes. (A) With cytosolic calcium ion increase, excitatory actions from astrocytes to neurons are likely to be initiated. These excitatory actions induce a reciprocal excitatory network between neurons, which results in neural circuit oscillations. (B) Calcium in astrocytes started to rise as early as 20 seconds before the onset of neuronal hyperactivity. Neuron-to-astrocyte action is also triggered and reciprocal interactions of neurons and astrocytes occur throughout the epileptic episode.
Credit
Ko Matsui
Usage Restrictions
Reporters may use freely these materials in news coverage with appropriate credit information.
License
Original content