Link between transcriptomic dysregulation and autism spectrum disorder. (IMAGE)
Caption
Genes involved in chromatin modification and gene transcription are associated with the progression of neurodevelopmental disorders. Researchers from Japan have developed a new mouse model to study the molecular mechanism behind the ability of KMT2C to cause autism spectrum disorder. They also showed that vafidemstat has a rescuing effect by normalizing disrupted gene expression.
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Tadafumi Kato from Juntendo University, Japan
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