Fracturing of cell junctions in response to cell stretching in claudin/JAM-A KO cells (IMAGE)

National Institutes of Natural Sciences

Fracturing of cell junctions in response to cell stretching in claudin/JAM-A KO cells

Caption

Cell-to-cell junctions were visualized by ZO1-GFP, and the dynamics of cell junctions were captured by movies. When the cells indicated by * were spontaneously stretched, a continuous belt of cell junctions was maintained in normal cells, while cell junctions fractured and fragmented in cells lacking claudin and JAM-A (00:24 ~ 02:48, h: min).

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Tetsuhisa Otani

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