Uncontrollable proliferation of TNBC cells via the excessive degradation of p27 by AIbZIP (IMAGE)

Hiroshima University

Uncontrollable proliferation of TNBC cells via the excessive degradation of p27 by AIbZIP

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Hiroshima University researchers found that AIbZIP is highly upregulated in triple negative breast cancer (TNBC). AIbZIP induces hyper proliferation of TNBC cells by promoting the degradation of p27, a negative regulator for cell proliferation.

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Atsushi Saito, Hiroshima University

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