Conformational change of MCI2III2IV2 (IMAGE)

Tsinghua University Press

Conformational change of MCI2III2IV2

Caption

  1. We solved the high-resolution structures of porcine MCI2III2IV2 in five conformations, State 1, State 2, Mid 1, Mid 2, and Mid 3.
  2. Two CIs found in constricted forms of MCI2III2IV2 were in deactive state, while two CIs in the expanded forms of MCI2III2IV2 were in either active or deactive state.
  3. The dynamic range of the 2Fe-2S cluster is related to the conformation of CI.
  4. Super-resolution gated stimulated emission depletion microscopy (gSTED) was applied to verify the in vivo existence of MCI2III2IV2.

Credit

Maojun Yang ,School of Life Science, Tsinghua University

Usage Restrictions

News organizations may use or redistribute this image, with proper attribution, as part of news coverage of this paper only.

License

Original content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.