Illustrations of ATTEC degrader technologies targeting different pathogenic biomolecules or organelles. (IMAGE)
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(A) Molecular glue ATTECs are targeting polyQ proteins in neurodegenerative disorders. (B) Bifunctional ATTECs targeting oncoprotein BRD4. (C) Bifunctional ATTECs targeting oncoprotein NAMPT. (D) Bifunctional ATTECs targeting oncoprotein CDK9/cyclin T1. (E) Bifunctional ATTECs targeting lipid droplets.
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