Substrate-induced droplet formation of a plant TIR domain in vitro. (IMAGE)

Max Planck Institute for Plant Breeding Research

Substrate-induced droplet formation of a plant TIR domain in vitro.

Caption

Substrate-induced droplet formation of a plant TIR domain in vitro. The Arabidopsis TIR domain protein RPP1 was fused with the fluorescent protein GFP so that the rapid droplet formation of the RPP1-GFP fusion protein can be visualized by fluorescence microscopy after addition of the substrates NAD+ or ATP in a test tube. The droplets are highly dynamic structures.

Credit

Wen Song and Li Liu

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