Role of STAP-1 in autoimmune disorders (IMAGE) Hokkaido University Caption The inflammatory reaction in spinal cords of STAP-1 knockout (KO) mice was less severe than that of wild type (WT) mice (top panels). In parallel, spinal cords of STAP-1 KO mice exhibited less demyelination—loss of the myelin sheath that surrounds nerves—when compared with those of WT mice (bottom panels). (Kota Kagohashi, et al. The Journal of Immunology. February 5, 2024) Credit Kota Kagohashi, et al. The Journal of Immunology. February 5, 2024 Usage Restrictions This image is copyrighted and may be used to report on this press release as long as the copyright holder is credited. License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.