Overview of the experimental setup (IMAGE) KeAi Communications Co., Ltd. Caption Step 1 was selecting the training cohort (n = 184) and the internal validation cohort (n = 62) by random seeds; Step 2 was selecting the optimal parameters through five times ten-fold cross-validation; Step 3 was the training of the final model with optimal parameters on the entire training data by the LR and ML ; Step 4 was validating the models of step 3 with the predictive ability and discrimination. GLM, Generalized linear model; LR, Logistic regression; ML, Machine learning; SVM, Support vector machines; RF, Random forests; ANN, Artificial neural networks; GBM, Gradient boosting machines; AUC, Areas under the receiver-operator characteristic curve. Credit Zi-Han Geng, et al. Usage Restrictions Credit must be given to the creator. Only noncommercial uses of the work are permitted. No derivatives or adaptations of the work are permitted. License CC BY-NC-ND Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.