Mutations in the Cu-Zn superoxide dismutase 1 gene SOD1 can cause familial amyotrophic lateral sclerosis (fALS) in a process that involves dissociation of the SOD1 dimer (IMAGE)

PLOS

Mutations in the Cu-Zn superoxide dismutase 1 gene SOD1 can cause familial amyotrophic lateral sclerosis (fALS) in a process that involves dissociation of the SOD1 dimer

Caption

Potential ALS therapeutic S-XL6 turns toxic Cu/Zn-superoxide dismutase monomers into stable dimers.

Credit

Ella Maru Studio (CC-BY 4.0, https://creativecommons.org/licenses/by/4.0/)

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Credit must be given to the creator.

License

CC BY

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