Digital seed amplification assays developed by Harvard researchers can detect and quantify minute amounts of a biomarker of Parkinson's disease (IMAGE)

Wyss Institute for Biologically Inspired Engineering at Harvard

Digital seed amplification assays developed by Harvard researchers can detect and quantify minute amounts of a biomarker of Parkinson's disease

Caption

In this version of their digital seed amplification assay (digital SAA), which first captures ⍺-synuclein aggregates on antibody-coated magnetic beads (illustration on the left), the team demonstrated the subsequent growth of individual ⍺-synuclein fibrils over 150 minutes in vitro (immunofluorescence images on the right).

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Wyss Institute at Harvard University

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