Fig. 1 (IMAGE)

Osaka University

Fig. 1

Caption

In human ES cell-derived cortical neurons (upper left), single-molecule CREB dynamics was observed (upper right). Activity-dependent repetitive CREB binding to DNA occurred at histone acetylation sites (lower left), where active RNAPII accumulation induces gene expression (lower right). Dashed lines indicate the outline of the nucleus. Scale bars: 50 µm (top left) and 5 µm (others).

Credit

Yuri Atsumi

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