How CD271-positive stem cells from adipose tissue can rescue limbs at risk of amputation (IMAGE)

Cincinnati Children's Hospital Medical Center

How CD271-positive stem cells from adipose tissue can rescue limbs at risk of amputation

Caption

Critical limb ischemia (CLI), the end-stage condition of peripheral artery disease (PAD), is increasing worldwide. Diabetes, smoking (Buerger disease), and auto-immune diseases all can cause CLI. A new study in Cell Reports Medicine led by experts at Cincinnati Children's and Kanazawa University in Japan shows, in mice, that transplanting human stem cells from fat tissue that are CD271-positive can restore blood flow by prompting new blood vessel growth. This graphic abstract illustrates the process. 

Credit

Cincinnati Children's and Cell Reports Medicine

Usage Restrictions

none

License

Original content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.