Cholesterol-Lowering Therapy May Hinder Aggressive Type of Colorectal Tumor (IMAGE)
Caption
Multiplex immunofluorescence image of cholesterol-rich human serrated colorectal cancer. Highly aggressive tumoral cells (green and magenta) are negative for both aPKCs (turquoise). The nuclear accumulation of SREBP2 (the major enzyme of cholesterol biosynthesis) is labeled in green, and nuclei in grey.
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Anxo Martinez-Ordoñez
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