Development of nanoparticle-based drug delivery system for inflammation treatment and diagnosis (IMAGE)
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Nanoparticles have been placed great expectations for inflammation targeting therapy. This review mainly elaborates on action mechanism of inflammation-targeting vectors, nanoparticle classification based on targeting moiety category, methods to combine targeting moiety with core nanoparticles, techniques for assessing targetability in vitro and in vivo and finally the challenges and prospects in this area, which would provide specific and practical guidance for researchers to construct and evaluate inflammation targeting vectors rationally.
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