siRNA effects (IMAGE) Picower Institute at MIT Caption A figure from the paper shows that an siRNA delivered by a lipid nanoparticle was able to reduce expression of the protein PU.1 and other related markers (IBA1, C1q, GFAP) in the brains of mice. The top row results are from an experimental control. The bottom row results illustrate the effect of the siRNA. Credit Langer/Tsai labs, MIT Usage Restrictions with credit License Original content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.