MAbID in a nutshell (IMAGE)

Hubrecht Institute

MAbID in a nutshell

Caption

MAbID in a nutshell. Left: antibodies, each binding a specific histone modification or protein, are merged with individual cells. After these antibodies have bound, a small barcode is attached to the adjacent DNA using the MAbID procedure. Right: these barcodes are then read, allowing the location of each histone modification on the DNA to be determined for each individual cell. This information allows the creation of cellular atlases that clearly identify the similarities and differences between cells.

Credit

Credit: Robin van der Weide. Copyright: Hubrecht Institute.

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