Vacuole Membrane Ion Channel Proteins (IMAGE)
Caption
Cartoon of the 3D models of the broad bean (right, pink-violet) and the thale cress (left, blue) TPC1 ion channel protein in the vacuole membrane. On the left, Calcium ions (red spheres) in the vacuole block the entrance to the channel pore and thus the transport of potassium ions (green spheres). Due to a natural variation in the amino acid sequence, the broad bean TPC1 channel pore is not blocked. The associated hyperactivity of the bean TPC1 directly affects the electrical properties of the vacuolar membrane.
Credit
Dirk Becker / University of Würzburg
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