Vacuole Membrane Ion Channel Proteins (IMAGE) University of Würzburg Caption Cartoon of the 3D models of the broad bean (right, pink-violet) and the thale cress (left, blue) TPC1 ion channel protein in the vacuole membrane. On the left, Calcium ions (red spheres) in the vacuole block the entrance to the channel pore and thus the transport of potassium ions (green spheres). Due to a natural variation in the amino acid sequence, the broad bean TPC1 channel pore is not blocked. The associated hyperactivity of the bean TPC1 directly affects the electrical properties of the vacuolar membrane. Credit Dirk Becker / University of Würzburg Usage Restrictions none License Original content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.