The formation mechanism of CR-hvKP and clinical presentation associated with CR-hvKP infection. (IMAGE)

Science China Press

The formation mechanism of CR-hvKP and clinical presentation associated with CR-hvKP infection.

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The formation of CR-hvKP is the result of the ongoing evolution of plasmids containing genes for carbapenem resistance or hypervirulence, with the help of IncF/IncN3 plasmid, E. coli, OMVs, etc. The clinical presentations of CR-hvKP include pyogenic liver abscesses, endophthalmitis, and meningitis caused by hvKP, as well as hospital-acquired urinary tract infections, pneumonia, septicemias, and soft tissue infections associated with CRKP.

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