Antibody to fight bacterial infections (IMAGE)

University of Cologne

Antibody to fight bacterial infections

Caption

Cryo-electron microscope reconstruction of the binding of a human anti-PcrV Fab antibody (yellow) to a PcrV pentamer (blue) of the type III secretion system (T3SS) of Pseudomonas aeruginosa. The antibody binding leads to an inhibition of the T3SS, which is an important virulence factor of P. aeruginosa.
 

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CSSB/Biao Yuan

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