Detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike RNA by in situ hybridization (ISH) in the retina (IMAGE)

Elsevier

Detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike RNA by in situ hybridization (ISH) in the retina

Caption

A-D: ISH for SARS-CoV-2 spike RNA (brown dots) primarily located in the outer nuclear layer of the retina (arrows, A) in case E22. Fewer positive signals are noted in the inner nuclear layer (A and B) and a retinal ganglion cell in case E23 (arrow, B). Panels A and B are with the SARS-CoV-2 spike RNA probe, and panels C and D are negative control probe for DapB. Scale bars = 20 mm. GCL, ganglion cell layer; INL, inner nuclear layer; ONL, outer nuclear layer

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The American Journal of Pathology

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