Base editing and chemical proteomics (IMAGE)

Scripps Research Institute

Base editing and chemical proteomics

Caption

Scripps Research scientists combined two methods to study cysteine residues in proteins previously linked to cancer. Using chemical proteomics (top), they learned which cysteines were accessible to drugs. Using genome editing (bottom), they analyzed the functional consequences of altering each cysteine. Together, they suggest which cysteines may be effective cancer drug targets. 

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Scripps Research

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