Atomic imaging and AI offer new insights into motion of parasite behind sleeping sickness
Peer-Reviewed Publication
Updates every hour. Last Updated: 23-Apr-2025 21:08 ET (24-Apr-2025 01:08 GMT/UTC)
African sleeping sickness is a serious infection caused by a parasitic microbe called Trypanosoma brucei.
Using an imaging technique called cryo-electron microscopy along with artificial intelligence, a team at the California NanoSystems Institute at UCLA mapped the hairlike flagellum that the microbe uses to propel itself, identifying 154 composite proteins.
Findings revealed that the parasite moves in a distinctive style, similar to a dragon boat, with unique adaptations that are essential to its ability to infect its hosts.
MIT engineers have fabricated a metamaterial that is not only strong but also stretchy. Their new method could enable stretchable ceramics, glass, and metals, for tear-proof textiles or stretchy semiconductors.
Scientists and space explorers have been on the hunt to determine where and how much ice is present on the Moon. Water ice would be an important resource at a future lunar base, as it could be used to support humans or be broken down to hydrogen and oxygen, key components of rocket fuel. University of Hawai‘i at Mānoa researchers are using two innovative approaches to advance the search for ice on the Moon.
One of the challenges of fighting pancreatic cancer is finding ways to penetrate the organ’s dense tissue to define the margins between malignant and normal tissue. A new study uses DNA origami structures to selectively deliver fluorescent imaging agents to pancreatic cancer cells without affecting normal cells. The study, led by University of Illinois Urbana-Champaign mechanical science and engineering professor Bumsoo Han and professor Jong Hyun Choi at Purdue University, found that specially engineered DNA origami structures carrying imaging dye packets can specifically target human KRAS mutant cancer cells, which are present in 95% of pancreatic cancer cases.
FAYETTEVILLE, Ark. — Microplastics, tiny plastic particles found in everyday products from face wash to toothpaste, are an emerging threat to health and ecology, prompting a research team to identify what keeps them trapped in stream ecosystems.