New research led by Queen Mary University of London and St Bartholomew's Hospital has shown that by using a combination of immunotherapy and chemotherapy the body's own immune system can be tuned to attack triple-negative breast cancer, extending survival
Less wealthy countries struggle to meet greater need with far fewer resources.
Heart patients are being advised to move around every 20 minutes in a bid to prolong life following a study presented at the Canadian Cardiovascular Congress (CCC) 2018.
Geneticists have assembled the largest sets of African genomic data available to date, creating a resource that will help researchers understand the genetic structure of Africa as well as the effects of genetic variation on protein function and disease. The findings underscore the importance of including globally diverse participant cohorts in genetics research, and were presented in a plenary session at the American Society of Human Genetics (ASHG) 2018 Annual Meeting in San Diego, Calif.
By studying the effect of genetic variations on lifespan across the human genome, researchers have devised a way to estimate whether an individual can expect to live longer or shorter than average, and have advanced scientific understanding of the diseases and cellular pathways involved in aging. Their findings were presented at the American Society of Human Genetics (ASHG) 2018 Annual Meeting in San Diego, Calif.
UTA researchers set out to determine whether pythons could have adapted to an extreme Florida freeze event in 2010. They generated data for dozens of samples before and after the freeze event. By scanning regions of the Burmese python genome, they identified parts of the genome that changed significantly between the two time periods, providing clear evidence of evolution occurring over a very short time scale in this population.
Mount Sinai Scientists developed a novel way to barcode and track different CRISPRs by utilizing synthetic proteins built from combinations of smaller proteins, called epitopes. By being able to mark each CRISPR with a unique identifier, the protein barcodes, or Pro-Codes for short, enable hundreds of CRISPRs to be used together to knockout a multitude of genes.
According to a first-of-its-kind international study, a new definition of Pediatric Acute Respiratory Distress Syndrome (PARDS) results in a more accurate diagnosis of many more children with the rapidly progressive disease than the widely used adult definition.
Upon implementing electronic medical record-based interventions, Boston Medical Center reduced unnecessary diagnostic testing and increased the use of postoperative order sets.
A special issue of the Human Factors and Ergonomics Society (HFES)'s Journal of Cognitive Engineering and Decision Making explores the competing perspectives on evidence-based medicine, best practices, and the quality movement in healthcare.