News by Subject Chemistry & Physics

Alzheimer's disease (AD) is the most common cause of dementia in elderly populations. Changes in the expression of the amyloid precursor protein (APP)-cleaving enzymes directly affect the formation of amyloid beta (Aβ) plaques, a neuropathological hallmark of AD.BACE1 mRNA level in AD subjects was significantly higher than those of healthy controls, whereas ADAM10 level was significantly lower in the AD subjects.

Patients who died of IS the most common type of dementia was vascular dementia while those died from other causes were most often diagnosed with Alzheimer's dementia (AD). Patients who died from IS and were registered in Riksstroke had higher MMSE score compared to other groups. Patients who died from IS took more cardiovascular medications. There were no differences in the use of antipsychotics, antidepressants, acetylcholinesterase inhibitors, memantine, anxiolytics, or hypnotics between the groups.

S. aureus under the biofilm mode of growth is often related to several nosocomial infections, more frequently associated with indwelling medical devices (catheters, prostheses, portacaths or heart valves).The present paper will provide an overview on the activity and potential applications of RIP as biofilm inhibiting compound, useful in the management of S. aureus biofilm infections.

Nanomedicine is a field of science that employs materials in the nanometer scale.Alzheimer's disease (AD) and Parkinson's disease (PD) are the most common disorders worldwide, becoming a serious economic burden and public health problem.In this review, we have highlighted the potential of lipid nanoparticles in reaching the brain, a challenging task in modern medicine.

Louis Populin and collaborators at the University of Wisconsin-Madison collaborators published a study this week in the Journal of Neuroscience describing increased connections between key parts of the brains of monkeys who have taken methylphenidate (Ritalin).