News by Subject Chemistry & Physics

A common and inexpensive drug may be used to counteract treatment resistance in patients with acute myeloid leukemia (AML), one of the most common forms of blood cancer. This is the conclusion of a study in mice and human blood cells performed at Karolinska Institutet and SciLifeLab and published in the medical journal EMBO Molecular Medicine. The researchers will now launch a clinical study to test the new combination treatment in patients.

The use of antipsychotics is associated with increased risks of head and brain injuries among persons with Alzheimer's disease, according to a recent study from the University of Eastern Finland. The risk increase was highest at the initiation of antipsychotic use. The results were published in the Journal of the American Geriatrics Society (JAGS).

Researchers have for the first time demonstrated what happens at the molecular level when two compounds known to inhibit crystal growth were combined, yielding new insights into malaria treatments and, more broadly, improving the process of drug development.

Researchers in Brazil evaluated cocaine and crack addicts undergoing rehabilitation for six months and observed a higher relapse rate and worse cognitive impairment among patients who smoked cannabis to try to mitigate their craving for cocaine.

As smokers know all too well, nicotine is highly addictive. It's hard to quit smoking, a habit that claims the lives of more than seven million people each year.

Purdue University researchers have designed a novel approach to use deep learning to better understand how proteins interact in the body - paving the way to producing accurate structure models of protein interactions involved in various diseases and to design better drugs that specifically target protein interactions.

Researchers have successfully created a non-fibrillating form of human insulin in a discovery that could improve the clinical delivery and cost of insulin for people living with diabetes.

Scientists have taken their cue from nature to provide new options for drug designers seeking to hold back the global threat of antimicrobial resistance. The scientists have blueprinted how two antibiotics produced by bacteria function against methicillin-resistant Staphylococcus aureus (MRSA) to pinpoint potential new drug targets.

Study shows Colorado drug SVC112 stops production of proteins that cancer stem cells need to survive and grow.