An international team led by a Skoltech researcher has developed a method of fabrication for biodegradable polymer microcapsules, made more efficient by turning to an unusual source of inspiration - traditional Russian dumpling, or pelmeni, making.
Nagoya University researchers and colleagues have uncovered a molecular pathway that enhances chemotherapy resistance in some pancreatic cancer patients. Targeting an RNA to interrupt its activity could improve patient response to therapy and increase their overall survival.
Optimizing manufacturing of rare precursors to drugs has implications in making medications more globally accessible, affordable Microbial production of drug precursors makes product cycle more sustainable Eliminating need for yew trees that take 80 years to grow makes development of taxol, an anti-cancer drug ingredient, possible for more companies
Hongbo Pang from the U of M College of Pharmacy found a better drug delivery system to treat prostate cancer and bone growth.
Aziridine structures are an important component of several medicines and pharmaceutical drugs, due to which reactions yielding desirable aziridine structures with high purity have received much interest. In a new study, scientists from Japan have reported a high yield of aziridines with high purity from oxazolones using a novel catalyst and look into the underlying mechanism, paving the way for future development of novel drugs and medicines.
Researchers used platinum and aluminum compounds to create a catalyst which enables certain chemical reactions to occur more efficiently than ever before. The catalyst could significantly reduce energy usage in various industrial and pharmaceutical processes. It also allows for a wider range of sustainable sources to feed the processes, which could reduce the demand for fossil fuels required by them.
A COVID-19 vaccine that could provide protection against existing and future strains of the COVID-19 coronavirus, and other coronaviruses, and cost about $1 a dose has shown promising results in early testing.
The objective of this research is to bring to the attention of public health officials, addiction medicine specialists, treatment officials, therapists, and the general public the alarming increase of dangerous toxic adulterants being added to street drugs and their potentially lethal synergistic effects. Also, to provide insights into how these new formulations can have serious pathophysiological effects on individuals with Substance Abuse Disorders (SUDs) during the COVID-19 pandemic.
More than 70% of neurological diseases, including Alzheimer's disease and the concussion-related disorder CTE, are believed to be fueled by protein clusters called tau aggregates. A new study sheds light on how they damage brain cells and could ultimately lead to new therapies for such "tauopathies."
* A new method has been developed to measure how fast amyloid fibrils grow. * The team fired a beam of neutrons at the growing fibrils then used a 'contrast matching' method that made most of each fibril invisible to neutrons, so they could analyse the signal from the growing end alone. * The method will help scientists better understand diseases associated with amyloid fibrils, such as Alzheimer's, Parkinson's and Type 2 diabetes.