News by Subject Chemistry & Physics

A CALCR cell found in mice may stop feeding without subsequential nauseating effects, as well as influence the long term intake of food.

A common and inexpensive drug may be used to counteract treatment resistance in patients with acute myeloid leukemia (AML), one of the most common forms of blood cancer. This is the conclusion of a study in mice and human blood cells performed at Karolinska Institutet and SciLifeLab and published in the medical journal EMBO Molecular Medicine. The researchers will now launch a clinical study to test the new combination treatment in patients.

MIT engineers have developed a light-sensitive material that allows gastrointestinal devices to be triggered to break down inside the body when they are exposed to light from an ingestible LED.

New Zealand media reports on chronic pain are focusing on treatments involving opioids and cannabis at the expense of best practice non-drug treatments, researchers have found.

The ISSCR is updating its Guidelines to respond to recent scientific advances that include the use of pluripotent stem cell (PSC) to create models of early human embryo development (see Stem Cell Reports 14:1-6). As the science continues to advance, it raises important scientific, clinical, ethical, and societal issues for researchers, regulators, and funding agencies. The ISSCR believes the scientific community must address these challenges to establish parameters for research in this area.

The Akay Lab biomedical research team at the University of Houston is reporting an improvement on a microfluidic brain cancer chip previously developed in their lab. The new chip allows quick assessment of the effectiveness of cancer drugs on brain tumors.

University of Colorado Cancer Center study shows that cancer-causing MLL gene may also push pluripotent stem cells to make hematopoietic stem cells, a strong step in the decades-long effort to make personalizable, durable blood stem cells.

For the first time, research shows that the contacts between cells, known as cell adhesion, are essential for cells to survive stress. The findings also suggest that impaired cell adhesion may sensitize cancer cells to drugs that damage cell proteins and cause stress.

The use of antipsychotics is associated with increased risks of head and brain injuries among persons with Alzheimer's disease, according to a recent study from the University of Eastern Finland. The risk increase was highest at the initiation of antipsychotic use. The results were published in the Journal of the American Geriatrics Society (JAGS).