Glowing pee may replace the biopsy needle: In detecting organ transplant rejection, a new nanoparticle has proven much faster and more thorough in the lab than a biopsy. When T cells mount their first attack on the organ's cells the nanoparticle sends an alarm signal into the urine that makes it fluoresce.
With their ability to treat a wide a variety of diseases, spherical nucleic acids (SNAs) are poised to revolutionize medicine. But before these digitally designed nanostructures can reach their full potential, researchers need to optimize their various components.
Cervical cancer could be eliminated as a public health problem in most countries by the end of the century by rapid expansion of existing interventions, according to a modelling study published in The Lancet Oncology journal.
Mining a large database of adverse reactions to medications, UC San Diego researchers found that people who took proton pump inhibitors (e.g., Prilosec, Nexium) for heartburn and acid reflux were more likely to experience kidney disease than people who took other forms of antacid.
A new study, published in The Journal of Clinical Investigation, establishes that the stress hormone epinephrine sets off a cascade of biochemical reactions that favor breast cancer growth and spread in chronically stressed patients.
Plants are master chemists, and Michigan State University researchers have unlocked their secret of producing specialized metabolites.
EPFL chemists have developed a light-based chemical method for cheap and simple production of chemical molecules used in drug discovery, such as muscle relaxants and antimicrobials.
Researchers at Duke University have shown that a single systemic treatment using CRISPR genome editing technology can safely and stably correct a genetic disease -- Duchenne muscular dystrophy (DMD) -- for more than a year in mice, despite observed immune responses and alternative gene editing outcomes.
Researchers at the Medical University of South Carolina discovered a new mechanism for a class of anti-cancer drugs known as E1 inhibitors. Their findings, published in Nature Communications on Dec. 4, 2018, reveal a novel binding site that will promote drug design of more efficient E1 inhibitors.
High cholesterol has been found to be a possible risk factor for the development of motor neurone disease (MND), according to a large study of genetic data led in the UK by Queen Mary University of London, in collaboration with the National Institutes of Health in the USA.