News by Subject Chemistry & Physics

Cryo-electron microscopy and computer simulations uncover how a cellular protein helps transport omega-3 fatty acids to the brain and eye, with implications for drug development.

Case Western Reserve University researchers studying prions--misfolded proteins that cause lethal incurable diseases--have identified for the first time surface features of human prions responsible for their replication in the brain.

In primary microcephaly, the ballet of cell division is dysregulated, preventing proper brain development. Scientists (UNIGE) have demonstrated how the mutation of a single protein, WDR62, prevents the proper formation of the cable network responsible for separating genetic material into two. As cell division is then slowed down, the brain does not have time to build itself completely. These results shed new light on cell division, a phenomenon also involved in cancer development.

Spectacular images of a molecule that shuttles omega-3 fatty acids into the brain may open a doorway for delivering neurological therapeutics to the brain.

A new therapy prompts immune defense cells to swallow misshapen proteins, amyloid beta plaques and tau tangles, whose buildup is known to kill nearby brain cells as part of Alzheimer's disease, a new study shows.

A discovery from researchers at the University of Illinois Chicago may lead to new treatments for individuals who suffer from alcohol use disorder and depression.