A new comprehensive natural history study about Amish nemaline myopathy (ANM) in the Old Order Amish population focuses on the promise of gene therapy for this lethal disorder. Amish nemaline myopathy (ANM) is an infantile-onset muscle disease linked to a mutation of the TNNT1 gene. The study summarizes genealogical records, clinical data, and molecular reports of one hundred and six ANM patients born between 1923 and 2017 and was led by researchers from the Clinic for Special Children in Strasburg, Pa.
Technologies and organizations should be redesigned to intermittently isolate people from each other's work for best collective performance in solving complex problems.
To encourage innovation in health care, governments need to move away from current siloed funding to funding that encourages collaboration among providers in managing patients who need care in a variety of settings, argue the authors of an analysis in CMAJ.
Women hold just 26 percent of executive-level positions in S&P 500 companies -- and sadly that is no accident, according to a new study by researchers in the University at Buffalo School of Management.
Online 'citizen science' data initiatives may be able to help map the distribution of rare species in the wild, according to a study published Aug. 8 in the open access journal PLOS ONE by Yifu Wang of McGill University and colleagues.
A team of LSU Health New Orleans researchers has found a lower prevalence of overweight and obesity among youth in Grenada compared to US adolescents. The differences may reflect the impact of the westernized diet and lifestyle. The research may lead to a change in worldwide obesity prevention strategy.
In times of economic difficulties, having to pay a child through college could be a major reason for a family to lose their home. This is according to two US researchers, Jacob Faber of New York University and Peter Rich of Cornell University, in a study published in Springer's journal Demography.
Political scientists in Konstanz and Berlin qualify the perception of Hitler as one of the most influential speakers in history through their extensive analysis of Adolf Hitler's election campaign appearances and election results between 1927 and 1933.
Leaders are more willing to take responsibility for making decisions that affect the welfare of others. In a new study, researchers at the University of Zurich identified the cognitive and neurobiological processes that influence whether someone is more likely to take on leadership or to delegate decision-making.
A study of firefighters in the United States breaks new ground in understanding how groups of workers -- especially those in high-risk occupations -- are able to take leaps of faith. The study conveys what goes into a person's ability to make critical trust-related judgments. It also has relevance and managerial implications in an era of declining trust in both people and institutions, the study's authors said.