Researchers show that procedures used to contain Candida auris infection in an animal facility can potentially be applied to hospitals and nursing homes to limit its spread.
Waterpipe tobacco smoking, otherwise known as 'hookah' or 'shisha,' is becoming increasingly popular worldwide, especially among youth. Traditional hookahs burn charcoal as a heat source, but recently, electrical heating elements (EHEs) have been introduced to the market. Reinforced by product advertising and package labeling, many hookah smokers believe that EHEs are less harmful than charcoal. Now, researchers report in ACS' Chemical Research in Toxicology that although EHEs reduce some toxicants, they increase others.
There are different pharmacological treatments for depression, mainly therapies that act on the serotonin system -- the so-called SSRIs (selective serotonin reuptake inhibitors). However, it has been evidenced that these antidepressants take around two weeks to have an effect and, what's more, around 30% of patients are resistant to this drug. Researchers of the Department of Human Physiology of the UMA Faculty of Medicine have taken a step closer to a new therapeutic target to face this mental disorder.
Neonatal exposure to nicotine alters the reward circuity in the brains of newborn mice, increasing their preference for the drug in later adulthood, report researchers at University of California San Diego School of Medicine in a published study.
Researchers in the UK have developed a new method for evaluating plutonium workers' historical internal radiation exposure in a study funded by the National Institute for Health Research. They focused their efforts on workers employed at the start of plutonium operations at the Sellafield (formerly Windscale) nuclear reprocessing facility in the UK.
Research at the Clemson University Center for Human Genetics is revealing new insights into how genes impact drug use and addiction through a novel study of susceptibility to the effects of cocaine and methamphetamine in fruit flies.
Pyrrolizidine alkaloids (PA) are natural constituents detected all over the world in more than 350 plant species and suspected to occur in more than 6,000. Plants produce them as a defence against predators. Out of more than 660 known PA and similar compounds, the 1,2- unsaturated PA in particular have a health-damaging potential. Consequently, they are undesired in foods and feeds.
Brazilian researchers combined cognitive dysfunction tests with an analysis of drug use patterns to identify patients at high risk of relapse after treatment.
In a unique, innovative experiment, researchers under the leadership of the University of Bern have investigated the effect of exhaust particles from aircraft turbine engines on human lung cells. The cells reacted most strongly to particles emitted during ground idling. It was also shown that the cytotoxic effect is only to some extent comparable to that of particles from gasoline and diesel engines.
Less chemotherapy is as effective at controlling disease for elderly or frail patients with advanced cancer of the stomach or oesophagus (food pipe), and leads to fewer side effects such as diarrhoea and lethargy. These are the results of a Cancer Research UK funded study, presented prior to the ASCO conference today (Wednesday).