A group of clinical neurologists, molecular biologists and computer scientists have worked together to solve the mystery of why motor neurons die in patients with motor neuron disease, published in Nature Communications this week.
A new University of Iowa-led study reports educational opportunities and higher incomes may be key to closing the health gap between most black and white Americans. Researchers say socioeconomic factors, mainly wealth and education, influenced the differences in health behaviors between the groups more than other variables.
National guidelines assume that all patients who're diagnosed with clinical sepsis in an emergency department will be admitted to the hospital for additional care, but new research has found that many more patients are being treated and released from the ED for outpatient follow-up than previously recognized.
A new technique to study fat stores in the body could aid efforts to find treatments to tackle obesity, research from the University of Edinburgh suggests. The approach focuses on energy-burning tissues found deep inside the body -- called brown fat -- that help to keep us warm when temperatures drop.
In response to antibiotics, a gene regulation network found in the bacterium Acinetobacter baumannii acts to boost both virulence and antibiotic resistance. Edward Geisinger of Tufts University School of Medicine and colleagues present new insights into this system in a study published in PLOS Pathogens.
Zika virus (ZIKV) has affected roughly half a million people in the Western hemisphere in recent years, including US veterans. Older veterans and those with comorbidities are at an increased risk of hospitalizations and neurological complications after a ZIKV infection, researchers now report in PLOS Neglected Tropical Diseases.
When George Brooks at UC Berkeley first began investigating lactate, or lactic acid, sports physiologists saw it as a muscle poison that lowered performance. His research over decades has reversed that picture, showing that it is the body's way of revving up for exercise or to fight disease. Clinicians are now planning clinical trials to use lactate to treat traumatic brain injury and a host of illnesses, including heart attacks, inflammation and swelling.
A novel adipokine that favors the development of insulin resistance and systemic inflammation has been identified by an international research team with participation of the DZD. In cases of severe obesity, this adipokine is secreted by the adipocytes of the abdominal fat tissue and released into the bloodstream. The new findings could contribute to the development of alternative approaches for the treatment of diseases caused by obesity.
Addressing a critical issue for people with a genetic disorder called tuberous sclerosis complex (TSC), doctors at The University of Texas Health Science Center at Houston (UTHealth) reported that a skin cream containing rapamycin significantly reduced the disfiguring facial tumors affecting more than 90 percent of people with the condition.
A new Tel Aviv University study identifies a previously unknown mechanism involved in the development of Lou Gehrig's disease, or amyotrophic lateral sclerosis (ALS). The findings could serve as the foundation for the treatment of ALS in the future.