New findings in mice suggest that the lack of a copy of the gene MVP may contribute to the symptoms of 16p11.2 deletion syndrome because it is needed for brain circuits to incorporate changes driven by experience.
The process that allows sounds experienced during infancy to shape language is poorly understood. Researchers at Nagoya University found that courtship behavior in Drosophila melanogaster can be shaped by earlier auditory experiences. Their findings allowed them to develop a novel and simple neurological model to study how experiences of sound can shape complex modes of communication in animals.
A comprehensive study on the rhythmicity of limpets -- mobile intertidal molluscs -- employing field and laboratory observations, as well assembling a clock oriented transcriptome -- shows that in the same way that these animals behave with a tidal rhythm, so too are a majority of their genes expressed in a tidal (and not circadian) rhythm, including some genes which were thought to play an important role in circadian clocks/timing.
Scientists at the John Innes Centre have come up with a novel way of quantifying cell shapes -- with a lot of mathematics and a little musical inspiration.
Professor CAI Gang from USTC and Professor Jacques Côté's team reports the 4.7 Å structure of the yeast NuA4/TIP60 complex, which elucidates the detailed architecture and molecular interactions between NuA4 subunits. A related study is published online in Nature Communications on March 19.
Bacteria produce proteins to take out specific competitors. One of these proteins can kill the hospital bacterium Pseudomonas aeruginosa. Microbial geneticists at KU Leuven, Belgium, have unravelled how this protein launches its attack and ensures that the bacteria die very quickly. In the long term, these proteins hold potential for new antibiotic cocktails.
A Norwegian biotech company called Phoenix Solutions AS is working with the Translational Genomics Research Institute (TGen), a Phoenix, Arizona-based biomedical research facility, to test the use of these pulsed sound waves to direct and focus cancer drug therapies.
Three tumor samples collected over time from a single patient shows how cancer evolves in response to treatment: A higher percentage of cancer stem cells in the final sample make a more aggressive disease.
Scientists have discovered a curious way for cells to die. In studying it, they are learning about how remnants of diseased cells are normally chewed up and removed.
Research from a UC Santa Cruz Genomics Institute-affiliated team just published in the journal Nature Biotechnology attempts to close huge gaps remain in our genomic reference map. The research uses nanopore long-read sequencing to generate the first complete and accurate linear map of a human Y chromosome centromere. This milestone in human genetics and genomics signals that scientists are finally entering a technological phase when completing the human genome will be a reality.