If chlamydiae want to multiply in a human cell, the first thing they need is a lot of glutamine. Würzburg researchers have clarified how the pathogenic bacteria obtain this substance.
The University of Kent's School of Biosciences and the Institute of Medical Virology at Goethe-University, Frankfurt am Main, have identified that a glycoprotein known as transferrin may critically contribute to severe forms of COVID-19.
Researchers from the University of Tsukuba found that the bacterium C. perfringens modulates the structure of its biofilm at different temperatures by regulating the expression of the novel extracellular protein BsaA. They showed the number of BsaA-producing cells decreases when the temperature increases from 25°C to 37°C, and BsaA-producing cells cover non-BsaA-producing cells to provide tolerance to external stresses. These findings help us understand how bacteria adapt to their environment to survive.
Scientists suggest that the initial impact of environmental toxins inhaled through the nose may induce inflammation in the brain, triggering the production of Lewy bodies that can then be spread to other brain regions. However, the relationship linking olfactory dysfunction and Parkinson's disease development remains unclear. New findings from a study add weight to this theory and identify a critical signaling molecule that may be key to the domino effect kicked off by nasal inflammation.
An international group of scientists published a paper, Aug. 1, 2020, in a special edition of the journal Biological Conservation that lays out an ambitious global conservation plan for parasites. A separate paper also found that the responses of parasites to environmental change are likely to be complex, and that a changing world probably will see both outbreaks of some parasites and a total loss of other parasite species.
In a recently published study, investigators from Brigham and Women's Hospital explore how the dynamics of bacterial species may influence the success of fecal microbiota transplantation in treating recurrent C. difficile infection. In Nature Communications, the team presents an algorithm to design personalized probiotic cocktails for patients with unhealthy gut microbiomes due to rCDI.
The first landmark study using next-generation technology to comprehensively examine contaminants in oysters in Myanmar reveals alarming findings: the widespread presence of human bacterial pathogens and human-derived microdebris materials, including plastics, kerosene, paint, talc and milk supplement powders.
An international team of researchers led by Aarhus University are the first to determine the crystal structure of an exopolysaccharide receptor. The results give insight into how plants and microbes communicate, and this knowledge can hopefully be used for more sustainable agriculture where microbes play an important role.
Melbourne researchers have revealed the multiple, intertwined cell death systems that prevent the spread of the 'intracellular' bacterium Salmonella, an important cause of typhoid fever which kills more than 100,000 people annually.
Researchers at the National Institutes of Health and other institutions have discovered another set of pore-like holes, or channels, traversing the membrane-bound sac that encloses the deadliest malaria parasite as it infects red blood cells. The channels enable the transport of lipids--fat-like molecules--between the blood cell and parasite, Plasmodium falciparum. The parasite draws lipids from the cell to sustain its growth and may also secrete other types of lipids to hijack cell functions to meet its needs.