California researchers have discovered that a medication used to prevent and treat malaria may also be effective for Zika virus. The drug, called chloroquine, has a long history of safe use during pregnancy, and is relatively inexpensive. The research was published today in Scientific Reports.
Patients experience pain and discomfort during active orthodontic treatment with fixed appliances. It can vary from person to person and is influenced by certain factors such as age, gender, previous pain experiences, stress or anxiety, and type of appliance.
Birth defects in babies born infected with Zika virus remain a major health concern. Now, scientists suggest the possibility that some women in high-risk Zika regions may already be protected and not know it. New research in PLOS Pathogens on Nov. 16, performed in mice, shows women who develop symptom-free Zika infections may be able to acquire immunity that would protect them from future infections and their offspring in a future pregnancy.
In a comprehensive and complex molecular study of blood samples from Ebola patients in Sierra Leone, published today (Nov. 16, 2017) in Cell Host and Microbe, a scientific team led by the University of Wisconsin-Madison has identified signatures of Ebola virus disease that may aid in future treatment efforts.
Researchers have uncovered a sequence of biological processes that occur in humans infected with the bacterium Mycobacterium tuberculosis as the infection progresses to pulmonary tuberculosis, according to new research published in PLOS Pathogens.
Protective antibodies from prior asymptomatic Zika infection defend against reinfection during pregnancy in mice, according to new research published in PLOS Pathogens.
Improved disease surveillance at Australian ports and borders could prevent the growing threat of dengue infection spreading across the country. A new QUT study has identified potential risk factors linked to dengue outbreaks beyond climatic conditions, including social factors, interstate and overseas travellers, rainwater tanks and economic status.
New approaches are needed to control the spread of epidemic diseases, according to the developers of a new model of the way pathogens can 'cooperate'. Their study examined the ways two pathogens work together, finding that cooperativity between contagion processes is likely to make the spread of contagious infections more severe.
Researchers at the University of California, Riverside have developed transgenic mosquitoes that stably express the Cas9 enzyme in their germline. The addition of Cas9 will enable the use of the CRISPR gene editing tool to make efficient, targeted changes to the mosquitoes' DNA. As proof of concept, the researchers used the system to disrupt cuticle, wing, and eye development, producing completely yellow, three-eyed and wingless mosquitoes. Their long-term goal is to develop new pest control strategies.
A new state-by-state health analysis in India finds that over two decades heart- and lung-related conditions, as well as other non-communicable diseases (NCDs), have surpassed infectious diseases, such as diarrhea and tuberculosis, as the nation's leading killers. The extent of this difference, however, varies significantly among the nation's 29 states and seven union territories.